Lead is a notorious heavy metal that accumulates in the bones, often replacing calcium in the bone matrix. This disruption can lead to weakened bone structures and inflammatory responses, resulting in osteitis. Cadmium, another heavy metal, impairs calcium metabolism and bone remodeling, which can also trigger inflammatory bone conditions. These metals can enter the body through contaminated water, air, and food, making it essential to monitor and mitigate their presence in the environment.