How does Fas (CD95) interact with other apoptotic pathways?
Fas (CD95) is not an isolated pathway but interacts with other apoptotic and survival pathways within the cell. Crosstalk between Fas signaling and pathways like the mitochondrial (intrinsic) apoptotic pathway can influence cell fate decisions. Additionally, the balance between pro-apoptotic and anti-apoptotic molecules, such as members of the Bcl-2 family, can modulate Fas-induced apoptosis. These interactions are crucial in determining cellular responses to toxic insults.
