What experimental models are used to study Fas (CD95) in toxicology?
Research on Fas (CD95) in toxicology employs various experimental models, including cell lines, animal models, and clinical studies. Transgenic mice deficient in Fas or FasL are commonly used to understand the role of Fas in vivo. These models help elucidate the consequences of altered Fas signaling in response to toxicants and provide valuable insights into potential interventions.