How Does the LDH Assay Compare to Other Cytotoxicity Assays?
The LDH assay is often compared to other cytotoxicity assays such as the MTT assay, trypan blue exclusion, and flow cytometry. Each method has its own strengths and weaknesses. For instance, while the MTT assay measures cell viability based on metabolic activity, the LDH assay provides a direct measure of cell membrane integrity. Combining multiple assays can offer a more comprehensive understanding of cytotoxic effects.
