Several methods and technologies are utilized to achieve targeting in toxicology:
Ligand-based targeting: This involves attaching a ligand to a drug or toxicant that has a high affinity for receptors on the target cells. These ligands can include antibodies, peptides, or small molecules. Nano-carriers: The use of nanoparticles and other nanoscale carriers can enhance the delivery of drugs to specific tissues while protecting them from degradation. Prodrugs: These are inactive compounds that are metabolized into active drugs within the target cells, thus localizing the drug's effect. Physical targeting: Methods like magnetic targeting, where drugs are conjugated with magnetic particles, can be directed to specific tissues using external magnetic fields.
