physiologically based pharmacokinetic (pbpk) models:

What are the Advantages of Using PBPK Models?

PBPK models offer several advantages:
- Mechanistic Insight: Provide a detailed understanding of the biological processes involved in the ADME of substances.
- Predictive Power: Can predict human responses based on animal data, reducing the need for animal testing.
- Flexibility: Can be adapted to different species, age groups, and disease states.
- Regulatory Acceptance: Increasingly accepted by regulatory agencies for risk assessment and drug approval processes.

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