Management of azole toxicity involves discontinuation of the offending agent and symptomatic treatment of adverse effects. In cases of severe hepatotoxicity, liver function should be closely monitored, and alternative antifungal therapy may be necessary. For drug interactions, adjusting the dose of the interacting medication or switching to a non-interacting alternative may be required.
In conclusion, azole antifungals are a critical component in the management of fungal infections. However, their use necessitates careful consideration of their toxicological properties, potential drug interactions, and specific patient factors. By understanding these aspects, healthcare providers can optimize treatment outcomes while minimizing risks.
