What are the Challenges in Studying Transcription Factors in Toxicology?
One of the primary challenges in studying transcription factors in toxicology is the complexity of their regulation and the redundancy in their pathways. Many transcription factors do not act alone but interact with other proteins and signaling pathways, which can complicate the analysis of their specific roles in toxicity. Additionally, the variability in transcription factor activity across different cell types and species adds another layer of complexity.