transcription factors

Which Transcription Factors Are Commonly Studied in Toxicology?


Some of the most commonly studied transcription factors in toxicology include AhR (Aryl hydrocarbon Receptor), Nrf2 (Nuclear factor erythroid 2-related factor 2), and NF-κB (Nuclear factor kappa-light-chain-enhancer of activated B cells). AhR is known for its role in responding to environmental pollutants such as dioxins, while Nrf2 is crucial in the defense against oxidative stress. NF-κB plays a significant role in the inflammatory response to toxic insults.

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