What are the guidelines for safe use of ketoconazole?
To minimize the risk of toxicity, ketoconazole should be used strictly according to prescribed guidelines. Monitoring liver function tests is essential, especially in long-term use. Patients should be educated about the symptoms of liver damage and advised to seek immediate medical attention if they experience symptoms such as yellowing of the skin or eyes, dark urine, or severe fatigue. It is also important to review all concurrent medications to avoid potential drug interactions.
