What are the primary toxicological concerns associated with ketoconazole?
One of the primary toxicological concerns with ketoconazole is its potential to cause hepatotoxicity. Hepatotoxicity refers to liver damage, and ketoconazole has been associated with severe liver injury, including cases of liver failure and even death. The risk of liver damage is dose-dependent and increases with prolonged use, making it crucial to monitor liver function regularly in patients undergoing treatment.
