What Are the Implications for Toxicological Studies?
In toxicological studies, mitochondrial mutations are a crucial factor to consider. They can modify an individual's response to toxicants, making some individuals more vulnerable to toxicity. For instance, certain mutations may predispose individuals to hepatotoxicity when exposed to specific drugs or chemicals. Understanding the role of mitochondrial genetics in toxicology can, therefore, help in predicting adverse effects and in the development of personalized medicine approaches.