What are the implications of RAD51 in genetic toxicity testing?
RAD51 is a valuable biomarker in genetic toxicity testing. Its expression levels and activity can indicate the extent and repair of DNA damage induced by various toxicants. Techniques such as Western blotting and immunofluorescence can be employed to assess RAD51 levels, providing insights into the genotoxic potential of substances. Moreover, RAD51 deficiency or malfunction can be a significant factor in individuals' susceptibility to toxic agents, impacting risk assessment and personalized medicine strategies.
