What Are the Long-term Toxicological Implications?
Long-term use of some antidiabetic drugs has potential toxicological implications. For instance, pioglitazone has been associated with an increased risk of bladder cancer, while prolonged use of SGLT2 inhibitors may lead to chronic kidney issues or bone density reduction. Regular monitoring and comprehensive patient education on the signs of toxicity are crucial for minimizing these risks. Healthcare providers must balance the benefits of glycemic control with possible adverse effects, adjusting treatment plans as necessary.