Antidiabetic medications can interact with other drugs, affecting their efficacy and safety:
Beta-blockers can mask hypoglycemia symptoms, complicating the management of blood sugar levels. Diuretics, especially thiazides, may reduce the effectiveness of some antidiabetic drugs by inducing hyperglycemia. Corticosteroids can increase blood glucose levels, requiring dose adjustments of antidiabetic medications. ACE inhibitors may enhance the hypoglycemic effect of insulin and sulfonylureas, increasing the risk of hypoglycemia.
