What Challenges Exist in Biopanning for Toxicology?
Despite its benefits, biopanning also faces challenges. One major challenge is the potential for non-specific binding, which can lead to false positives. Additionally, the conditions used in vitro during biopanning may not perfectly mimic the in vivo environment, affecting the relevance of the selected peptides. Overcoming these challenges requires careful optimization of the biopanning process and validation of results in biological systems.
