vitamin k cycle

What Role Does the Vitamin K Cycle Play in Toxicology?

In the context of toxicology, the vitamin K cycle is particularly important when considering the effects of anticoagulant rodenticides, such as warfarin and superwarfarins. These substances inhibit the VKOR enzyme, leading to a decrease in active vitamin K and, consequently, impaired blood clotting ability. Understanding the cycle helps in assessing the toxicological impact and in designing appropriate treatment strategies for poisonings.

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