Several types of assays are used in HTS, each designed to evaluate different aspects of toxicity:
Cell Viability Assays: These assays measure the effect of compounds on cell survival and proliferation. Genotoxicity Assays: These tests assess the potential of compounds to cause genetic mutations or damage. Enzyme Inhibition Assays: These assays evaluate the ability of compounds to inhibit or activate specific enzymes, which can be indicative of toxic effects. Receptor Binding Assays: These tests measure the interaction of compounds with specific cellular receptors, which can affect cell function and viability.
