What Are the Therapeutic Interventions Targeting ADHs?
Therapeutic interventions targeting ADHs include the use of enzyme inhibitors to prevent the metabolism of toxic alcohols. For instance, fomepizole is a competitive inhibitor of ADH and is used in the treatment of methanol and ethylene glycol poisoning. This inhibition prevents the formation of toxic metabolites, allowing for their excretion unchanged. Understanding the pharmacokinetics and pharmacodynamics of such interventions is essential for effective clinical management.
