In toxicology, understanding immunogenicity is crucial for several reasons:
Drug Development: Immunogenicity can impact the safety and efficacy of biopharmaceuticals. It is essential to evaluate potential immune responses during preclinical and clinical testing. Vaccine Safety: Vaccines aim to be immunogenic to confer protection against diseases. However, excessive or unintended immune responses can lead to adverse effects. Environmental Toxicants: Certain chemicals and environmental agents can modulate the immune system, leading to hypersensitivity, autoimmune disorders, or immunosuppression.