Why is Spatial Arrangement Important in Toxicology?
The importance of spatial arrangement in toxicology lies in its influence on the pharmacokinetics and pharmacodynamics of substances. A molecule's shape can affect its ability to pass through cell membranes, interact with enzymes, and bind to receptors. For instance, enantiomers—molecules that are mirror images of each other—can have very different effects in the body. One enantiomer might be therapeutically beneficial, while the other could be toxic.