Why Is the Citric Acid Cycle Important in Toxicology?
The cycle is central to cellular respiration, and its disruption can lead to significant metabolic consequences. Certain toxic substances, such as heavy metals or specific drugs, can inhibit enzymes within the cycle, leading to energy deficits and cellular dysfunction. By understanding the cycle, toxicologists can better predict how toxicants might interfere with cellular energy production and identify potential biomarkers for exposure.
