How Can Autophagy Be Targeted for Therapeutic Interventions?
Targeting autophagy offers a promising strategy for therapeutic interventions in various diseases, including cancer, neurodegenerative disorders, and infectious diseases. By modulating autophagic pathways, it is possible to enhance the clearance of toxic aggregates, improve cell survival, or promote cell death in cancer cells. Researchers are actively exploring autophagy modulators, such as rapamycin and metformin, for their potential to treat diseases associated with autophagic dysfunction.