Autophagy is intimately involved in the cellular response to drug-induced toxicity. Some drugs can induce autophagy as a survival mechanism, aiding in the clearance of toxic metabolites and damaged cellular components. For instance, the antimalarial drug chloroquine is known to inhibit autophagy, which can lead to increased cellular stress and toxicity. Conversely, promoting autophagy in certain contexts can help mitigate drug toxicity, making it a potential therapeutic target in pharmacology.
