Can NF-κB inhibitors be used therapeutically in toxicology?
Given NF-κBâs involvement in disease states associated with inflammation and cancer, its inhibitors are being investigated as potential therapeutic agents. In toxicology, NF-κB inhibitors could potentially mitigate damage from toxic exposures by reducing inflammation and oxidative stress. However, the challenge lies in selectively targeting NF-κB pathways without compromising its essential roles in normal immune function. Current research is focused on developing specific inhibitors that can modulate NF-κB activity with minimal side effects.
