In toxicology, the study of Nrf2 activators is crucial due to their role in enhancing the body's defense mechanisms against toxic insults. By boosting the expression of detoxification enzymes and antioxidant proteins, Nrf2 activators can mitigate the adverse effects of various toxicants, including heavy metals, environmental pollutants, and pharmaceutical drugs. This makes them a valuable tool in developing therapies for diseases linked to oxidative stress and toxicity.
