What are the implications of 8-Oxoguanine in human health?
The presence of 8-oxoguanine in DNA is associated with various health implications. It has been implicated in the pathogenesis of cancer, where oxidative DNA damage can lead to mutations that drive tumor development. Additionally, 8-oxoguanine accumulation is linked to neurodegenerative disorders such as Alzheimer's and Parkinson's diseases, highlighting its role in aging and disease progression. Thus, understanding and mitigating the effects of 8-oxoguanine are critical for improving health outcomes.
