CYP1A2 is involved in the metabolism of several important drugs, including caffeine, theophylline, and some antipsychotics. The enzyme's activity can influence the pharmacokinetics of these drugs, affecting their clearance from the body, and ultimately their efficacy and toxicity. Variability in CYP1A2 activity, due to genetic polymorphisms or environmental factors, can lead to significant differences in how individuals respond to certain medications.
