How Can TFIIH Be Targeted for Therapeutic Interventions?
Research into TFIIH has opened avenues for developing therapeutic interventions, particularly in cancer treatment. By understanding how TFIIH contributes to DNA repair, scientists aim to design drugs that can modulate its activity. Inhibiting TFIIH in cancer cells, for example, can enhance the efficacy of chemotherapeutic agents by preventing the repair of DNA damage induced by these drugs, thus promoting the death of cancerous cells.